The Endoscopy Center of New York
201 East 93rd Street
New York, NY 10128
(212) 897-1006
Saurabh Mehandru, M.D.

Icahn Building
1425 Madison Avenue, Box 1069
New York, NY 10029

Dr. Mehandru straddles the world of clinical care and laboratory based investigation. He graduated from the University College of Medical Sciences, Delhi University, India and then completed residency training in Internal Medicine at the NYU School of Medicine where he also served as Medical Chief Resident. He received subspecialty training in Clinical Gastroenterology at The Icahn School of Medicine at Mount Sinai.

Dr. Mehandru undertook post-doctoral training at the Rockefeller University, first working in the Laboratory of Dr. David Ho (with Dr. Martin Markowitz) and then in the Laboratory of Dr. Ralph Steinman, Nobel Laureate in Physiology or Medicine (2011).

During this period, Dr. Mehandru, reported on the preferential depletion of gut lymphocytes during acute HIV-1 infection and on the lack of immune reconstitution in the GI tract following years of apparently suppressive antiretroviral therapy.

After finishing his post-doctoral training, Dr. Mehandru was invited to join the faculty at Mount Sinai where in addition to serving as an Assistant Professor of Gastroenterology, he leads a laboratory of Mucosal Immunology since 2013. Dr. Mehandru’s research interests include mucosal trafficking, the host-pathogen interface, dendritic cell biology and mucosal immunopathology in primary and acquired immunodeficiency states. He is an NIH-funded investigator who has received multiple awards.

Clinical Focus

  • Angiodysplasia of the Colon
  • Antibiotic-Associated Colitis-C Difficile
  • Barrett's Esophagus
  • Celiac Disease
  • Chronic Pancreatitis
  • Colon Polypectomy
  • Colon Polyps
  • Colonoscopy
  • Colorectal Cancer
  • Constipation
  • Crohn's Disease
  • Diarrhea
  • Dyspepsia
  • Dysphagia
  • Enteral Feeding
  • Esophageal Cancer
  • Familial Adenomatous Polyposis
  • Flexible Sigmoidoscopy
  • Gallstones
  • Gastritis
  • Inflammatory Bowel Disease
  • Iron-Deficiency Anemia
  • Irritable Bowel Syndrome
  • Jaundice
  • Malabsorption
  • Pancreatic Cancer
  • Pancreatitis
  • Peptic Ulcer
  • Percutaneous Endoscopic Gastrostomy
  • Rectal Cancer
  • Short Bowel Syndrome
  • Stomach Cancer
  • Ulcerative Colitis
  • Upper GI Endoscopy

Research Topic
AIDS/HIV, Aging, Antigen Presentation, Autoimmunity, B Cells, Cell Adhesion, Cell Biology, Cellular Immunity, Chemokines, Cytokines, Dendritic Cells, Epithelial Cells, Gene Expressions, Hepatitis C Virus, Immune Deficiency, Immunology, Immunosuppression, Infectious Disease, Inflammation, Integrins, Knockout Mice, Lung, Lymphocytes, Macrophage, Microarray, Mucosal Immunology, Retinoic Acid, Retrovirus, T Cells, Trafficking

Multi-Disciplinary Training Area
Immunology [IMM]

MBBS, University College of Medical Sciences

Residency, Internal Medicine
Bellevue Hospital

Fellowship, Gastroenterology
Mount Sinai Hospital